- 04 марта 2014, 22:56
- PNAS USA
Intestinal CD103− dendritic cells (DCs) are pathogenic for colitis. Unveiling molecular mechanisms that render these cells proinflammatory is important for the design of specific immunotherapies. In this report, we demonstrated that mesenteric lymph node CD103− DCs express, among other proinflammatory cytokines, high levels of osteopontin (Opn) during experimental colitis. Opn...